Genetic testing

1. Genetic testing increases lipid-lowering therapy use in humans (statin 95% vs 83%, combination 52% vs 30%).

   Human trialpremature ACS with LDL-C >= 4 mmol/L15 months

   Opportunistic Genetic Testing for Familial Hypercholesterolemia in Premature Acute Coronary Syndrome: Results of the ACCURATE Study

   JACC. Advances·7 Aug 2026

1. Genetic testing increases LDL-C target attainment in humans (73% vs 53% (P = 0.04)).

   Human trialpremature ACS with LDL-C >= 4 mmol/L15 months

   Opportunistic Genetic Testing for Familial Hypercholesterolemia in Premature Acute Coronary Syndrome: Results of the ACCURATE Study

   JACC. Advances·7 Aug 2026

1. Genetic testing decreases low-density lipoprotein cholesterol in humans (1.65 mmol/L vs 1.93 mmol/L (P = 0.03)).

   Human trialpremature ACS with LDL-C >= 4 mmol/L15 months

   Opportunistic Genetic Testing for Familial Hypercholesterolemia in Premature Acute Coronary Syndrome: Results of the ACCURATE Study

   JACC. Advances·7 Aug 2026

More on Low-density lipoprotein cholesterol

1. Genetic testing increases familial hypercholesterolemia diagnosis in humans (10% vs 0%).

   Human trialpremature ACS with LDL-C >= 4 mmol/L15 months

   Opportunistic Genetic Testing for Familial Hypercholesterolemia in Premature Acute Coronary Syndrome: Results of the ACCURATE Study

   JACC. Advances·7 Aug 2026