There are 7 papers on intraepithelial neoplasia in aging research: 2 trials and 2 observational studies in people, 2 in animals.
7 papers study it103 more mention it1 finding
13 new papers in 30 daysSee all 110
- Human trial2
- Humans2
- Animals1
- Model organisms1
Upstream
1JAK–STAT signaling
upin flies1
1 study
JAK–STAT signaling
upin flies1
JAK–STAT signaling induces intraepithelial neoplasia in flies (chronic activation of JAK/Stat signaling).
“induces a metaplasia of the gastric epithelium, CCR decline, and subsequent commensal dysbiosis and epithelial dysplasia along the GI tract.”
Model organismschronic activation of JAK/Stat signalinggastrointestinal tract
Cell host & microbe
Funding
3 grants since 2018Fogarty International Center$372KNational Institute for Health Research£1.3MNational Cancer Institute$658K
Latest
57 papers in 12 monthsEuropean Journal of Cancer
Combined pharmacologic and lifestyle intervention for breast cancer prevention: Results of the randomized phase II TOLERANT trial in high-risk women
Randomized trial in 110 peopleLifestyle intervention
JCI Insight
Human Y chromosome pan-organ mapping reveals progressive mosaic loss from normal to cancer
Cohort study of 405 peopleBiomarkers
Nature Communications
Performance of artificial intelligence-assisted cytology and high-risk human papillomavirus testing for cervical cancer screening
Cross-sectional study of 284,002 peopleCervical cancer
Frontiers in Cellular and Infection Microbiology
Dynamic Alterations of the Oral-Gut Microbiome during Colorectal Adenoma Progression and Their Clinical Associations
Accepted, not yet published: study in peopleBiomarkers
International Journal of Gynaecology and Obstetrics
Comparison of self-sampling versus clinician-sampling HPV DNA cervical cancer screening in South African women living with and without HIV
Cross-sectional study of 903 peopleCervical cancer
Advanced Science
Noninvasive Detection and Subtyping of Esophageal Cancer by Circulating Cell-Free mtDNA Fragmentomics: A Multi-Center Validation Study
Cross-sectional study of 1,260 peopleEsophageal adenocarcinoma
NEJM AI
Closing the Automation Gap in HPV-Based Cervical Cancer Screening: Independent External Validation of an AI Model for Dual-Stain Triage
Cross-sectional study of 9,006 peopleCervical cancer
BMC Medicine
Comparative validation and local adaptation of gastric cancer risk assessment models in a large multicenter endoscopic screening cohort in China
Cohort study of 144,329 peopleGastric cancer
bioRxiv
HPV-Associated Tonsillar Intraepithelial Neoplasia and Oral High-Risk HPV mRNA as a Candidate Biomarker
Preprint: cross-sectional study of 1,180 peopleBiomarkers
Cancers
Metformin as an Adjunct to Fertility-Sparing Treatment in Atypical Endometrial Hyperplasia and Early-Stage Endometrioid Endometrial Cancer: Narrative Review
Systematic review of studies in peopleMetformin