Epileptogenesis
2 papers2 findings
Associations
1Inflammation
upin humans1upin reviews1
2 studies
Inflammation
upin humans1upin reviews1
Inflammation raises the risk of epileptogenesis.
“Collectively, these processes establish a self-amplifying neurovascular inflammatory loop that may contribute to epileptogenesis in aging.”
Review
Preprints.org30 Jun 2026Preprint
Inflammation is associated with epileptogenesis in humans.
“aging-related reductions in seizure threshold, vascular dysfunction, neurodegenerative processes, and immune dysregulation ("inflammaging") all contribute to epileptogenesis”
Reviewin older adults
The Saga of Late-Onset Unexplained Epilepsy
Epilepsy currents20 May 2026
Latest
8 in 12 monthsThe European Journal of Neuroscience
Somatic Mosaicism of the Brain: The Functional Implications of Post-Zygotic Mutations to Neural Circuits
ReviewMechanisms
Lancet
Natural history and clinical impact of epilepsy in adults with Down syndrome: a multicentre clinical study
Cohort study of 4,804 peopleDown syndrome
Experimental Neurology
Age-related trajectories in epileptogenesis and neurological function in an experimental model of post-traumatic epilepsy
Experiments in miceMechanisms
bioRxiv
Comprehensive transcriptomic and proteomic profiling of mTOR-related epilepsy
Preprint: cross-sectional study of 60 peoplemTOR signalling