Early-onset type 2 diabetes

1. SLC30A8 is associated with early-onset type 2 diabetes in humans.

   Humansearly-onset T2D (AAO < 55 years)

   Genome-Wide Association Analyses Identify Distinct Genetic Architectures for Extreme Early-Onset and Late-Onset T2D · Diabetes, obesity & metabolism · 8 Sep 2026

SLC30A8 →

1. Early-onset type 2 diabetes is associated with SNP-based heritability in humans (11.2% vs. 6.4%).

   Humansearly-onset T2D vs. late-onset T2Dn = 74,795

   Genome-Wide Association Analyses Identify Distinct Genetic Architectures for Extreme Early-Onset and Late-Onset T2D · Diabetes, obesity & metabolism · 8 Sep 2026

SNP-based heritability →