Early-onset diseases

Disease

1 paper1 finding

  • Humans1

Associations

1

Offspring number

downin humans1

1 study
  1. Early-onset diseases are associated with offspring number in humans.

    “But for early-onset diseases, the pattern reverses, indicating reproductive costs of early morbidity.”

    HumansAffected versus unaffected individuals with high polygenic disease risk

    Genetic trade-offs in fertility and longevity explain the maintenance of disease-associated alleles in humans

    Nature ecology & evolution21 Jul 2026

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