Dementia or mild cognitive impairment

Disease

1 paper1 finding

  • Humans1

Associations

1

Environmental risk score

upin humans1

1 study
  1. Environmental risk score raises the risk of dementia or mild cognitive impairment in humans.

    “Midlife F1 score was associated with increased dementia or MCI risk in NHW APOE ε4 no‐carriers.”

    Humansin Non-Hispanic White APOE ε4 non-carriers

    Midlife and Later‐Life Environmental Risk Scores (ERSs) Modify the Associations of Apolipoprotein E ( APOE ) ε4 with Dementia

    AAIC 2025 abstractDec 23, 2025

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Drug Design, Development and Therapy

GLP-1 agonists linked to lower dementia risk after COVID-19

GLP-1 receptor agonist initiation was associated with a lower hazard of incident dementia than DPP-4 inhibitors (HR 0.64) in diabetic COVID-19 survivors.GLP-1 receptor agonist initiation was associated with a lower hazard of incident dementia than DPP-4 inhibitors (HR 0.64) in diabetic COVID-19 survivors.

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Frontiers in Aging Neuroscience

COVID-19 tied to higher dementia risk in older adults with diabetes

Older adults had an overall dementia hazard ratio of 1.51 after documented infection compared with matched uninfected peers across up to six years of follow-up.Older adults had an overall dementia hazard ratio of 1.51 after documented infection compared with matched uninfected peers across up to six years of follow-up.

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