Corneal neovascularization

1. IL-1β mediates corneal neovascularization in humans (completely inhibited).

   “either interleukin-1 receptor antagonist or anti-IL-1β neutralization completely inhibited the promotion of senescent fibroblasts in vascular tube formation in vitro and CNV in vivo.”

   Animalsinhibition of IL-1β in senescent fibroblastscornea

   Autocrine IL-1β mediates the promotion of corneal neovascularization by senescent fibroblasts

   American journal of physiology. Cell physiology·29 Aug 2018

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