Colonic senescence

1 paper

Animals1

Latest

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International ImmunopharmacologyJul 30

Dehydrodiisoeugenol ameliorates DSS-induced ulcerative colitis by suppression of cellular senescence through inhibiting AKT and activating GSK3B

Experiments in miceInterventions

bioRxivJun 4

Gut Microbiota-derived Acetate Safeguards the Colonic Epithelial Acetyl-CoA Reserve to Avert Colonic Senescence

Preprint: experiments in miceGut and microbiome

Nature CommunicationsMar 1

Targeting NAT10 alleviates colonic senescence and elderly-onset colitis by disrupting N4-acetylation of DYRK1A

Study in peopleCellular senescence

Toxicology and Applied PharmacologyFeb 11

Protective effect of Florfenicol against DSS-induced ulcerative colitis by inhibiting cellular senescence and reducing inflammation via the AMPK signaling pathway

Experiments in miceInterventions

International ImmunopharmacologyNov 17

Retapamulin alleviates DSS-induced ulcerative colitis via direct AMPK activation and modulation of the gut microbiota-metabolite axis

Experiments in miceGut and microbiome

The Journal of Pharmacology and Experimental TherapeuticsAug 22

Network pharmacology and experimental validation reveal clotrimazole alleviates dextran sulfate sodium-induced ulcerative colitis by inhibiting intestinal senescence

Experiments in miceGut and microbiome

Toxicology and Applied PharmacologyAug 1

Miconazole alleviates colitis by suppressing colonic senescence, NF-κB Signaling and gut microbiota modulation

Experiments in animalsGut and microbiome

International ImmunopharmacologyAug 17

Network pharmacology and experimental verification revealing valnemulin alleviates DSS-induced ulcerative colitis by inhibiting intestinal senescence

Experiments in miceGut and microbiome

International ImmunopharmacologyMay 23

Tedizolid phosphate alleviates DSS-induced ulcerative colitis by inhibiting senescence of cell and colon tissue through activating AMPK signaling pathway

Experiments in miceGut and microbiome

Nature CommunicationsOct 1

Heat-inactivated Bifidobacterium adolescentis ameliorates colon senescence through Paneth-like-cell-mediated stem cell activation

Experiments in miceGut and microbiome