1 paper1 finding
CG25144382
upin humans1
CG25144382 is associated with cognitive impairment but not dementia in humans (1.3% higher, p = 5.1x10-5).
“The site cg25144382, which is not annotated to a gene, had 1.3% higher methylation in prevalent CIND ( p = 5.1x10‐5)”
Humanscross-sectionalbloodn = 3,395
AAIC 2025 abstract24 Dec 2025
Cognitive impairment developed in 6.7% of participants with the disorder, compared with 3.4% without it, in a cohort of adults aged 50 and older.Cognitive impairment developed in 6.7% of participants with the disorder, compared with 3.4% without it, in a cohort of adults aged 50 and older.
In 1,780 Latinos, diagnostic AUCs reached 0.70 to 0.75 for mild cognitive impairment and 0.83 to 0.84 for dementia across Spanish and English testing.In 1,780 Latinos, diagnostic AUCs reached 0.70 to 0.75 for mild cognitive impairment and 0.83 to 0.84 for dementia across Spanish and English testing.