CG25144382

1. CG25144382 predicts cognitive impairment in humans (1.8% higher, p = 1.3x10-5).

   “1.8% higher methylation in incident impairment ( p = 1.3x10‐5)”

   Humansprospective, up to 4 years follow-upbloodup to 4 yearsn = 2,424

   DNA methylation‐wide association study of prevalent and incident dementia in the US Health and Retirement Study

   AAIC 2025 abstract·24 Dec 2025

More on Cognitive impairment

1. CG25144382 is associated with dementia in humans (2.7% higher, p = 6.0x10-5).

   “2.7% higher methylation in prevalent dementia ( p = 6.0x10‐5)”

   Humanscross-sectionalbloodn = 3,395

   DNA methylation‐wide association study of prevalent and incident dementia in the US Health and Retirement Study

   AAIC 2025 abstract·24 Dec 2025

More on Dementia

1. CG25144382 is associated with cognitive impairment but not dementia in humans (1.3% higher, p = 5.1x10-5).

   “The site cg25144382, which is not annotated to a gene, had 1.3% higher methylation in prevalent CIND ( p = 5.1x10‐5)”

   Humanscross-sectionalbloodn = 3,395

   DNA methylation‐wide association study of prevalent and incident dementia in the US Health and Retirement Study

   AAIC 2025 abstract·24 Dec 2025

More on Cognitive impairment but not dementia