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Cardio-metabolic disorders

Disease

2 papers study it7 more mention it3 findings

  • Humans2

Effects

1

Whole-brain QRI

upin humans1

1 study

  1. Cardio-metabolic disorders increase whole-brain QRI in humans (F = 24.69, p = 6.82 × 10−7).

    “CMD (F = 24.69, p = 6.82 × 10−7 ) significantly, independently impacted whole-brain QRI in SMI+.”

    Humansin SMI+n = 665

    The additive impact of cardio-metabolic disorders and psychiatric illnesses on accelerated brain aging

    Human brain mappingFeb 3, 2022

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Associations

2

Plasma biomarkers

upin humans1

1 study

  1. Plasma biomarkers predict cardio-metabolic disorders in humans (AUC > 0.7).

    “They were verified to have good diagnostic value for CMDs in aging with an AUC > 0.7.”

    Humansaging with CMDsplasman = 30

    Multiplex proteomics identifies inflammation-related plasma biomarkers for aging and cardio-metabolic disorders

    Clinical proteomicsApr 22, 2024

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MMP-1

upin humans1

1 study

  1. Cardio-metabolic disorders are associated with MMP-1 in humans (28 DEPs).

    “Twenty-eight DEPs were found in elderly individuals with CMDs and MMP1 was the most differentially expressed hub protein in CMDs.”

    Humanscardio-metabolic disordersplasman = 30

    Multiplex proteomics identifies inflammation-related plasma biomarkers for aging and cardio-metabolic disorders

    Clinical proteomicsApr 22, 2024

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