Whole-brain QRI

1. Hypertension increases whole-brain QRI in humans (d = 0.19 (SMI+), d = 0.14 (SMI-)).

   “Hypertension had a significant effect on SMI+ (d = 0.19) and SMI- (d = 0.14).”

   HumansSMI+ (d = 0.19) and SMI- (d = 0.14)

   The additive impact of cardio-metabolic disorders and psychiatric illnesses on accelerated brain aging

   Human brain mapping·Feb 3, 2022

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1. Cardio-metabolic disorders increase whole-brain QRI in humans (F = 24.69, p = 6.82 × 10−7).

   “CMD (F = 24.69, p = 6.82 × 10−7 ) significantly, independently impacted whole-brain QRI in SMI+.”

   Humansin SMI+n = 665

   The additive impact of cardio-metabolic disorders and psychiatric illnesses on accelerated brain aging

   Human brain mapping·Feb 3, 2022

More on Cardio-metabolic disorders

1. Severe mental illness increases whole-brain QRI in humans (F = 40.47, p = 2.06 × 10−10).

   “SMI (F = 40.47, p = 2.06 × 10−10 ) and CMD (F = 24.69, p = 6.82 × 10−7 ) significantly, independently impacted whole-brain QRI in SMI+.”

   Humansn = 1,618

   The additive impact of cardio-metabolic disorders and psychiatric illnesses on accelerated brain aging

   Human brain mapping·Feb 3, 2022

More on Severe mental illness