Bone disease

Disease1 paper

Humans1

Trial sponsors

National Heart, Lung, and Blood Institute
2 trialsPhase 3
RenJi Hospital
1 trialPhase 3478 people
University of Alberta
1 trialPhase 2120 people
National Institute of Dental and Craniofacial Research
1 trialPhase 29 people
Mark Pegram
1 trialPhase 1/28 people

Latest

10

Frontiers in ImmunologyReview16 min

Osteoimmune senescence in aging bone: from inflammaging dogma to cell-type-specific therapeutic windows

Scientific ReportsIn silicoYesterday

An attention-based CNN–Transformer hybrid framework for osteoporosis and osteopenia classification in knee X-ray images

Frontiers in ImmunologyReview2 Oct

The potential role and research progress of the gut microbiota-NGF axis in postmenopausal bone homeostasis imbalance

Microbiome composition

PharmaceuticsReview28 Sep

Surface-Engineered Phytochemical Nanomedicines for Postmenopausal Osteoporosis: Skeletal Targeting, Imaging-Supported Evaluation, and Therapeutic Performance

Postmenopausal osteoporosis

BiomoleculesAnimals26 Sep

Nuciferine reduces ovariectomy-induced bone loss in rats by activating autophagy

The lotus leaf alkaloid promoted bone formation and osteogenic differentiation in ovariectomized rats through the TFEB autophagy-lysosomal pathway.The lotus leaf alkaloid promoted bone formation and osteogenic differentiation in ovariectomized rats through the TFEB autophagy-lysosomal pathway.

Bones and joints

International Journal of NanomedicineReview8 Sep

Harnessing Natural Extracellular Vesicles to Combat Age-Related Diseases: From Aging Drivers to Therapeutic Opportunities

Applied SciencesCells6 Sep

Aging Reprograms the Signaling, Metabolic, and Gene Regulatory Dynamics in Murine Bone Marrow-Derived Mesenchymal Stem Cells

MAPK/ERK signalling

Sichuan Da Xue Xue Bao Yi Xue BanReview3 Sep

[Research Advances on Mechanisms and Interventions of DNA Methylation-Regulated Aging-Related Imbalance in Bone Metabolism]

Epigenetic regulation of gene expression

BiomedicinesAnimals27 Aug

Chronic THC Inhalation During Early Adulthood Exacerbates Ovariectomy-Induced Bone Loss in a Rat Model of Osteoporosis

Bones and joints

Food & FunctionAnimals26 Aug

Pearl mussel (Hyriopsis cumingii)-derived exosome-like nanovesicles promote osteogenesis and alleviate ovariectomy-induced bone loss in mice

Bones and joints