Basal pancreatic ductal adenocarcinoma

Disease

1 paper1 finding

  • Humans1

Associations

1

Loss of the Y chromosome

upin humans1

1 study
  1. Loss of the Y chromosome is associated with basal pancreatic ductal adenocarcinoma in humans.

    “with strong enrichment in advanced disease and, critically, in the basal subtype”

    Humanspancreatic ductal adenocarcinomapancreatic tumormales

    Y chromosome loss linked to advanced pancreatic cancer

    bioRxiv7 Oct 2026Preprint

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bioRxiv

Y chromosome loss linked to advanced pancreatic cancer

Across two cohorts, about 50% of male patients with pancreatic ductal adenocarcinoma had lost the Y chromosome, an alteration enriched in advanced disease.Across two cohorts, about 50% of male patients with pancreatic ductal adenocarcinoma had lost the Y chromosome, an alteration enriched in advanced disease.

Preprint: study in peopleMechanisms