B-cell lymphoma
2 papers3 findings
- Humans1
Effects
2T cell aging
upin reviews1
1 study
T cell aging
upin reviews1
B-cell lymphoma increases T cell aging.
“lymphoma accelerates T cell aging by transcriptional and epigenetic reprogramming that mirrors physiological aging.”
ReviewT cell
Unraveling lymphoma-induced immune senescence
Cancer cell21 Aug 2025
Age-associated transcriptional, epigenetic, and phenotypic alterations in T cells
upin mice1
1 study
Age-associated transcriptional, epigenetic, and phenotypic alterations in T cells
upin mice1
B-cell lymphoma induces age-associated transcriptional, epigenetic, and phenotypic alterations in T cells in mice.
“lymphoma alone is sufficient to trigger transcriptional, epigenetic, and phenotypic alterations in young T cells that manifest in aged T cells.”
AnimalsB cell lymphomaT cell
Lymphoma accelerates T cell and tissue aging
Cancer cell21 Aug 2025
Associations
1Age-associated transcriptional, epigenetic, and phenotypic alterations in T cells
upin humans1
1 study
Age-associated transcriptional, epigenetic, and phenotypic alterations in T cells
upin humans1
B-cell lymphoma is associated with age-associated transcriptional, epigenetic, and phenotypic alterations in T cells in humans.
“lymphoma alone is sufficient to trigger transcriptional, epigenetic, and phenotypic alterations in young T cells that manifest in aged T cells.”
HumansB cell lymphomaT cell
Lymphoma accelerates T cell and tissue aging
Cancer cell21 Aug 2025
Trial sponsors
Company3 trialsPhase 4440 people
Company2 trialsPhase 2168 people
Company1 trialPhase 2100 people
Company1 trialPhase 242 people
Company1 trialPhase 229 people
Company2 trialsPhase 1/2380 people
Company1 trialPhase 1/2803 people
Company1 trialPhase 1/2150 people