Arterial stiffening

1 paper

Humans1

Latest

16 in 12 months

Acta Biomaterialia4 Oct

Human aortic elastin degrades with age in males but not females

In 17 human thoracic aorta samples, elastin stiffness, straightness, and lamellar length decreased significantly with age in males (p < 0.05) but not females.In 17 human thoracic aorta samples, elastin stiffness, straightness, and lamellar length decreased significantly with age in males (p < 0.05) but not females.

Cross-sectional study of 17 peopleMechanisms

American Journal of Physiology Regulatory, Integrative and Comparative Physiology2 Oct

Aged perivascular fat worsens aortic stiffness in mice

Ex vivo tests in young and old mice showed that intact perivascular fat increased aortic stiffness only in older animals, alongside higher fat collagen levels.Ex vivo tests in young and old mice showed that intact perivascular fat increased aortic stiffness only in older animals, alongside higher fat collagen levels.

Experiments in animalsMechanisms

Research Square26 Sep

Mediating role of arterial stiffness and hemodynamic load in the association between obesity and cardiovascular disease risk: a prospective cohort study

Preprint: cohort study of 5,584 peopleMechanisms

Frontiers in Cardiovascular Medicine18 Sep

Perimenopause as a potential window of cardiometabolic remodeling in heart failure with preserved ejection fraction: a missed opportunity for prevention

ReviewMechanisms

Journal of Clinical Medicine13 Aug

Muscle Strength as a Key Independent Predictor of Arterial Stiffness and Metabolic Syndrome in Aging Mexicans: Unveiling the Sarcopenic Obesity Paradox

Cross-sectional study of 2,087 peopleArterial stiffness

Aging and Disease11 Aug

Metformin: A Promising Candidate for Slowing the Progression of Cardiovascular Aging

ReviewMetformin

Life28 Mar

Correlation of Early Vascular Aging Ambulatory Score with Kidney Damage in a Hypertensive Population: A Pilot Study

Cross-sectional study of 50 peopleHypertension

International Journal of Molecular Sciences28 Mar

Shear-Calibrated High-Intensity Interval Training to Promote Endothelial Autophagy and Delay Vascular Senescence: A Biomarker-Guided Approach

ReviewHigh-intensity interval training

Journal of Inflammation Research26 Mar

Colchicine Alleviates Non-Atherosclerotic Vascular Aging by Targeting Endothelial Dysfunction and Inflammatory Status

Experiments in miceInterventions

The Journal of Physiology21 Feb

Age-related decline in NCKX4-mediated calcium clearance accelerates aortic remodelling and drives early vascular ageing

Experiments in miceExtracellular matrix remodelling