Age-related midgut hyperplasia

1. Early midgut injury prevents age-related midgut hyperplasia in flies.

   “early midgut injury prevents the abrupt onset of aging hyperplasia and extends lifespan in flies.”

   Model organismsmidgut

   Age mosaic of gut epithelial cells prevents aging

   Nature communications·22 Jul 2025

More on Early midgut injury

1. enterocyte turnover induces age-related midgut hyperplasia in flies.

   “the abrupt onset of aging hyperplasia is due to the collective turnover of developmentally generated "old" enterocytes (ECs).”

   Model organismscollective turnover of developmentally generated old enterocytesmidgut

   Age mosaic of gut epithelial cells prevents aging

   Nature communications·22 Jul 2025