Age-associated cognitive decline

2 papers

Animals2

Latest

10 in 12 months

NPJ Dementia8 Oct

Alzheimer's disease neuropathological characterization of the dog brain and relationship to biofluid biomarkers and cognitive function

Study of 24 dogsAlzheimer's disease

Molecular Brain8 Oct

Forced treadmill running and ladder climbing physical activity attenuates cognitive decline and protein aggregates in aged 3xTg-AD mice

Experiments in miceInterventions

Journal of Alzheimer's Disease30 Sep

Aging dogs exhibit heterogeneous cognitive decline trajectories: A longitudinal comparative model

Study of 92 dogsPopulations

Research Square4 Sep

Young Ovary Factors Transfer Female Cognitive Resilience to the Aged Male Brain

Preprint: experiments in miceReproductive system

bioRxiv20 Aug

Lymphatic CD49a is a driver of meningeal immune aging and cognitive decline

Preprint: experiments in miceImmune response

Nature12 Mar

Intestinal interoceptive dysfunction drives age-associated cognitive decline

Experiments in miceCognitive decline

ACS Medicinal Chemistry Letters29 Jan

Discovery of Potent, Selective, and Brain-Penetrant Small Molecule CD38 Inhibitors

Experiments in animalsInterventions

Age and Ageing23 Jan

Can dual-task high-velocity exercise training improve cognitive function in older adults? Secondary analysis of an 18-month cluster randomized controlled trial

Randomised trial in 300 peopleInterventions

PNAS9 Jan

ACSS2 upregulation enhances neuronal resilience to aging and tau-associated neurodegeneration

Experiments in miceInterventions

Molecular Neurobiology28 Nov

Integrated Aerobic Exercise and Multisensory Environment Training for Age-related Cognitive Decline via Hippocampal-prefrontal Neural Circuit Modulation

Experiments in miceCombined aerobic and resistance training