Urate

Biomarker4 papers1 finding

Human trial1
Humans2
Model organisms1

Interventions

1

Dapagliflozin

downin humans1Moderate certainty

1 study

Dapagliflozin decreases urate in humans (P-interaction < 0.001).
Human trialPAH or CTEPH on background vasodilator therapyserum10 mg daily12 weeksn = 52
Dapagliflozin in pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension: The DAPAH randomized controlled trial · The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 31 Aug 2026

Dapagliflozin →

Latest

16

Research SquareHumansPreprint15 h

Uric acid salt linked to high-risk plaque in heart arteries

In an observational study of 116 patients, detected urate was linked to odds of high-risk plaque 4.91 times those without detected urate.In an observational study of 116 patients, detected urate was linked to odds of high-risk plaque 4.91 times those without detected urate.

Research SquareHumansPreprintYesterday

A Calibrated Glycaemic-Blind Machine-Learning Model for Opportunistic Prediabetes Screening in UK Biobank

Advances in RheumatologyReview2 Oct

Effects of SGLT2 inhibitors on gout-related and cardiometabolic outcomes in patients with type 2 diabetes mellitus: a scoping review

SGLT2 inhibitors

BMJ Military HealthHumans30 Sep

Difference in the prevalence of metabolic syndrome components between male pilots of the Republic of Korea Air Force and the general Korean male population: a cross-sectional comparative study

Metabolic syndrome

International Journal of General MedicineHumans28 Sep

Nonlinear Association Between Serum Uric Acid and Incident Stroke in Patients with Diabetes: A Two-Centre Cohort Study

Medical SciencesReview24 Sep

SGLT2 Inhibitors in Nephrolithiasis: Emerging Evidence and What Urologists Need to Know

SGLT2 inhibitors

Nutrition, Metabolism, and Cardiovascular DiseasesReview21 Sep

Time to redefine serum uric acid levels in women: A call for sex-specific cardiometabolic risk thresholds

Frontiers in NutritionHumans18 Sep

Insulin resistance and uric acid-related metabolic disturbances jointly identify individuals at high risk of advanced cardiovascular-kidney-metabolic syndrome: a population-based study

Cardiovascular-kidney-metabolic syndrome

Journal of Clinical HypertensionHumans16 Sep

Associations of Genetic Variants in Uric Acid Transporter Genes With Salt Sensitivity, Longitudinal Blood Pressure Changes, and Incident Hypertension in Chinese Adults

Frontiers in EndocrinologyHumans15 Sep

Early urate-lowering therapy and cardiometabolic risk in adults without documented major cardiometabolic disease: a real-world cohort study