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uPAR expression

There are 3 papers on uPAR expression in aging research: 1 observational study in people, 2 in animals. The newest story, Oct 26, 2026: “Targeted drug carriers reduced artery calcium buildup in mice”.

Biomarker

3 papers study it2 more mention it2 findings

1 new paper in 30 daysSee all 5

  • Humans1
  • Animals2

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2

Alzheimer's disease-like pathology

upin mice1

1 study

  1. Alzheimer's disease-like pathology increases uPAR expression in mice (5xFAD compared with WT mice).

    “uPAR expression increased with age and was significantly elevated in 5xFAD mice”

    Animals5xFAD compared with WT micebrain

    uPAR exhibits age- and region-dependent expression in the brains of mice with Alzheimer's disease-like pathology

    Brain research

More on Alzheimer's disease-like pathology

Age

upin mice1

1 study

  1. Age increases uPAR expression in mice.

    “uPAR expression increased with age and was significantly elevated in 5xFAD mice”

    Animalsbrain

    uPAR exhibits age- and region-dependent expression in the brains of mice with Alzheimer's disease-like pathology

    Brain research

Latest

Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 1Apr 2026: 0May 2026: 1Jun 2026: 0Jul 2026: 1Aug 2026: 0Sep 2026: 0Oct 2026: 1Nov 2026: 04 papers in 12 months
ESC Congress 2026 Abstract

Targeted drug carriers reduced artery calcium buildup in mice

Tiny carriers delivered two cell-clearing drugs in two mouse models, improving survival and avoiding blood-cell side effects associated with dasatinib given without…Tiny carriers delivered two cell-clearing drugs in two mouse models, improving survival and avoiding blood-cell side effects associated with dasatinib given without carriers.

Mouse studyInterventions
Paper
Journal of Controlled Release

Targeted drug carriers proposed for obesity in mice

The experimental carriers combined two drugs intended to remove senescent cells, which have stopped dividing, and targeted cells with high levels of a surface protein.The experimental carriers combined two drugs intended to remove senescent cells, which have stopped dividing, and targeted cells with high levels of a surface protein.

Mouse studyObesity
Paper

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