Type I/III collagen

Biomarker

1 paper2 findings

  • Animals1

Interventions

1

Atelocollagen

upin mice1

1 study
  1. Atelocollagen increases type I/III collagen in mice.

    “These effects led to decreased NF-κB activity and MMP1/3/9 expression, increased SMAD2/3 phosphorylation, and upregulated type I/III collagen synthesis in senescent HDFs and aged mouse skin.”

    Animalsskin

    Atelocollagen Increases Collagen Synthesis by Promoting Glycine Transporter 1 in Aged Mouse Skin

    International journal of molecular sciences7 Dec 2025

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Upstream

1

SLC6A9

is required forin mice1

1 study
  1. SLC6A9 is required for type I/III collagen in mice.

    “All beneficial effects were blocked by GlyT1 inhibition and were generally superior to glycine alone.”

    Animalsatelocollagen treatment in senescent HDFs and aged mouse skin

    Atelocollagen Increases Collagen Synthesis by Promoting Glycine Transporter 1 in Aged Mouse Skin

    International journal of molecular sciences7 Dec 2025

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