Tumor-infiltrating immune cells
3 papers study it9 more mention it2 findings
- Cells1
- In silico1
Upstream
1Cellular senescence
downin humans1
1 study
Cellular senescence
downin humans1
Cellular senescence decreases tumor-infiltrating immune cells in humans.
“Older patients may have lower levels of TIICs infiltration due to age-related immune senescence particularly T cell function, which can limit the effectivity of cancer immunotherapies.”
Reviewcancer
Aging-related biomarker discovery in the era of immune checkpoint inhibitors for cancer patients
Frontiers in immunology
Associations
1Senescence-related gene signature score
downin silico1
1 study
Senescence-related gene signature score
downin silico1
Senescence-related gene signature score is associated with tumor-infiltrating immune cells in silico.
“SRG signature scores negatively correlated with tumor-infiltrating immune cells”
In silico
Head & neck
Latest
4 papers in 12 monthsCritical Reviews in Oncology/hematology
Bidirectional roles of senescence in tumor-infiltrating immune cells: Mechanisms, impact on immunotherapy, and therapeutic strategies
ReviewImmune response
Journal for Immunotherapy of Cancer
Tumor-associated macrophages educated by IGSF9 exhibit a senescence-associated secretory phenotype to promote tumor immune escape
Experiments in miceSenescence-associated secretory phenotype (SASP)
Frontiers in Immunology
Aging-related biomarker discovery in the era of immune checkpoint inhibitors for cancer patients
ReviewImmune response
Pathologie
Tumor-immune cell interaction and senescence-associated molecules in colorectal carcinoma
Cohort study of 598 peopleImmune response