Cellular senescence-related gene risk score

1. Cellular senescence-related gene risk score decreases overall survival in silico (P<0.05).

   “In the TCGA-colon adenocarcinoma (COAD) and GEO-COAD cohorts, the high-risk group was associated with a bleaker forecast (P<0.05)”

   In silicocolon adenocarcinoma

   Senescence-related signatures predict prognosis and response to immunotherapy in colon cancer

   Journal of gastrointestinal oncology·Jun 27, 2024

1. Cellular senescence-related gene risk score is associated with immune response in silico.

   “ssGSEA results indicated that the high-risk group was associated with tumor-infiltrating immune cells, including MDSCs, macrophages and Tregs.”

   In silicohigh-risk group in glioma

   Comprehensive Analysis Uncovers Prognostic and Immunogenic Characteristics of Cellular Senescence for Gliomas

   Research Square·Nov 23, 2022Preprint

More on Immune response

1. Cellular senescence-related gene risk score predicts mortality in silico.

   “The independence of the risk score as a prognostic indicator was validated by KM analysis, ROC analysis, PCA analysis, and immunohistochemical results.”

   In silicoin glioma patients

   Comprehensive Analysis Uncovers Prognostic and Immunogenic Characteristics of Cellular Senescence for Gliomas

   Research Square·Nov 23, 2022Preprint

1. Cellular senescence-related gene risk score predicts survival time in silico.

   “Patients with the low-risk score group had a longer survival time, while the high-risk score group is the opposite.”

   In silicogastric cancer

   Cellular Senescence-Related Genes: Predicting Prognosis in Gastric Cancer

   Frontiers in genetics·Jun 1, 2022