Triacylglyceride accumulation
1 paper1 finding
- Model organisms1
Interventions
1Trametinib
downin flies1
1 study
Trametinib
downin flies1
Trametinib decreases triacylglyceride accumulation in flies.
“trametinib, mitigates several of the detrimental effects of a high-sugar diet by reducing TAG accumulation, restoring TAG composition, and increasing survival.”
Model organismshigh-sugar diet
Pharmacological protection from a sugar-rich diet through inhibition of Ras/MAPK signaling
iScience22 Sep 2026