Tissue-resident memory T cell abundance

Older age is associated with tissue-resident memory T cell abundance in humans.

“Ageing was associated with a selective reduction of tissue-resident memory T (Trm) cells”

Humansindependent of effector T cell numbers, inflammageing levels or frailtynasal mucosa

Ageing of the Upper Airway Epithelial Niche Limits Tissue-Resident T Cell Immunity

bioRxiv (Cold Spring Harbor Laboratory)·16 Jul 2026Preprint