Annals of Neurology
Frontotemporal dementia linked to faster aging on a DNA clock
Patients scored 1.17 higher than controls on a blood DNA measure of accelerated aging in an adjusted analysis of two observational cohorts.Patients scored 1.17 higher than controls on a blood DNA measure of accelerated aging in an adjusted analysis of two observational cohorts.
Meta-analysisFrontotemporal dementia
Who was studiedPeople with frontotemporal dementia and controls
What changedDNA-clock age acceleration was approximately 1.2 years higher in people with frontotemporal dementia than in controls
The catchSmoking-related DNA changes partly explain the higher aging-clock estimates