Temporal lobe tau
1 paper studies it20 more mention it1 finding
- Humans1
Associations
1Study-partner-reported apathy
upin humans1
1 study
Study-partner-reported apathy
upin humans1
Study-partner-reported apathy is associated with temporal lobe tau in humans.
“AES-I was significantly associated with beta-amyloid and temporal lobe tau, and the associations were retained after further adjusting for depressive symptoms.”
Humansolder adults across cognitive spectrum (cognitively unimpaired, MCI, dementia)n = 170
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry
Funding
1 grant since 2018National Institute on AgingUS$431.8k
Latest
13 papers in 12 monthsBrain Communications
A vascular component to the selective vulnerability of the medial temporal lobe to tau pathology
Cohort study of 151 peopleMechanisms
bioRxiv
Mesoscale medial temporal lobe connectivity patterns relate to tau pathology and memory in older adults
Preprint: cohort study of 75 peopleMechanisms
AAIC 2025 Abstract
Lower resting‐state phasic locus coeruleus activity is associated with cortical tau accumulation and cognitive decline in preclinical Alzheimer's disease
Cohort study of 92 peopleMechanisms
AAIC 2025 Abstract
BrainAge moderates associations between AD biomarkers and cognitive decline: findings from A4/LEARN and the Harvard Aging Brain Study
Cohort study of 1,690 peopleBiomarkers
AAIC 2025 Abstract
Heterogeneity in tau onset, patterns and accumulation rates are explained by age of amyloid onset
Cohort study in peopleMechanisms
AAIC 2025 Abstract
Exploring the Cross‐sectional Association of Mood Symptoms with Subjective and Objective Cognition in the A4 study
Cross-sectional study of 447 peoplePopulations
AAIC 2025 Abstract
Specific functional patterns of the locus coeruleus and cognitive decline in preclinical Alzheimer's disease: associations with tau and astrocyte reactivity
Cohort study of 92 peopleMechanisms
AAIC 2025 Abstract
Tau spatial distribution predicts domain‐specific cognitive performance: a machine learning approach
Cohort study of 529 peopleBiomarkers
AAIC 2025 Abstract
Tau spatial distribution predicts domain‐specific cognitive performance: a machine learning approach
Cohort study of 529 peopleBiomarkers
AAIC 2025 Abstract
Lower resting‐state phasic locus coeruleus activity is associated with cortical tau accumulation and cognitive decline in preclinical Alzheimer’s disease
Cohort study of 92 peopleMechanisms