1 paper1 finding
Ruxolitinib
downin mice1
Ruxolitinib decreases telomere dysfunction in mice.
“alleviated chronic bone deterioration, diminished telomere dysfunction, lowered senescence and SASP marker expression and reduced bone-marrow adiposity.”
Animalspost-radiotherapymales
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research8 Aug 2026
National Heart, Lung, and Blood InstituteUS$2.4mNational Institute of Environmental Health SciencesUS$1.1mNational Cancer InstituteUS$693.1k
Aging and Telomere Dysfunction in the Intestinal Stem Cell Niche
National Institute on AgingUniversity of PennsylvaniaUS$333.1k2025–2026
Lung Remodeling Mediated by Telomere Dysfunction in Alveolar Type II Cells
National Heart, Lung, and Blood InstituteUniversity of California, San FranciscoUS$799.5k2018–2027
Telomere dysfunction driven molecular outputs in the cardiac unit
National Institute of Environmental Health SciencesUniversity of Pittsburgh at PittsburghUS$566k2024–2028
Determine how telomere dysfunction impacts neuronal function
National Cancer InstituteDivision of Basic Sciences - NciUS$693.1k
In lab-grown human fibroblasts, tiny vesicles from senescent cells prompted dividing cells to halt division and activate a DNA damage response.In lab-grown human fibroblasts, tiny vesicles from senescent cells prompted dividing cells to halt division and activate a DNA damage response.