Systemic and organ-specific proteomic aging acceleration

1. Major depressive disorder is associated with systemic and organ-specific proteomic aging acceleration in humans.

   “A lifetime history of MDD was associated with accelerated proteomic aging at both systemic and organ-specific levels-including the brain-in both cohorts”

   HumansLifetime history of major depressive disorder; both cohorts

   Biological aging acceleration in major depressive disorder: a multi-omics, multi-modal analyses

   Research square·28 May 2025Preprint

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