Subtle-seq read enrichment

downregulated differentially expressed genes are associated with Subtle-seq read enrichment in Paramecium cells.

“Transcriptome analysis identified downregulated differentially expressed genes (DEGs) in aged cells, and Subtle-seq reads enriched in or around these genes.”

Cellsin or around downregulated differentially expressed genes

Subtle-seq reveals frequent ageing-associated chromosome fragmentation on nucleosome core DNA

Nucleic acids research·20 Mar 2026