Aging·Mar 10MicroRNA-18a prevents senescence of mesenchymal stem cells by targeting CTDSPLExperiments in human cellsCellular senescencePaper
Science China Life Sciences·Jan 4CRL2APPBP2-mediated TSPYL2 degradation counteracts human mesenchymal stem cell senescenceExperiments in human cellsCellular senescencePaper
Biomedicine & Pharmacotherapy·Jan 2Hyaluronan delays human amniotic epithelial stem cell senescence by regulating CD44 isoform switch to activate AKT/mTOR signalsExperiments in human cellsInterventionsPaper
Frontiers in Cell and Developmental Biology·Dec 19Cellular microenvironment: a key for tuning mesenchymal stem cell senescenceReviewCellular senescencePaper
Bioactive Materials·Nov 29Magnesium-containing bioceramics stimulate exosomal miR-196a-5p secretion to promote senescent osteogenesis through targeting Hoxa7/MAPK signaling axisExperiments in ratsMagnesiumPaper
Chemico-biological Interactions·Nov 25Phytic acid improves osteogenesis and inhibits the senescence of human bone marrow mesenchymal stem cells under high-glucose conditions via the ERK pathwayExperiments in animalsBones and jointsPaper
Small·Nov 10Senescence-Targeted and NAD⁺-Dependent SIRT1-Activated Nanoplatform to Counteract Stem Cell Senescence for Promoting Aged Bone RegenerationExperiments in animalsBones and jointsPaper
ACS Nano·Nov 10Micronano Titanium Accelerates Mesenchymal Stem Cells Aging through the Activation of Senescence-Associated Secretory PhenotypeExperiments in ratsSenescence-associated secretory phenotype (SASP)Paper
International Journal of Molecular Medicine·Nov 8Single‑cell sequencing, genetics, and epigenetics reveal mesenchymal stem cell senescence in osteoarthritis (Review)ReviewCellular senescencePaper
Acta Neuropathologica Communications·Oct 20Myopathologic trajectory in Duchenne muscular dystrophy (DMD) reveals lack of regeneration due to senescence in satellite cellsCohort study of 24 peopleCellular senescencePaper
Cell Stem Cell·Oct 14Genome-wide CRISPR activation screening in senescent cells reveals SOX5 as a driver and therapeutic target of rejuvenationExperiments in human cellsInterventionsPaper
Cellular and Molecular Life Sciences·Oct 13Silencing circSERPINE2 restrains mesenchymal stem cell senescence via the YBX3/PCNA/p21 axisExperiments in human cellsInterventionsPaper
Research Square·Oct 10FKBP5 drives bone marrow stem cells senescence and suppresses osteogenic differentiation via canonical WNT/β-catenin signaling pathwayPreprint: experiments in human cellsWnt/β-catenin signalingPaper
Heliyon·Oct 9TRAF3IP2 drives mesenchymal stem cell senescence via regulation of NAMPT-mediated NAD biosynthesisExperiments in human cellsNAD+ metabolismPaper
Stem Cell Research & Therapy·Oct 9Blockade of TGF-β signalling alleviates human adipose stem cell senescence induced by native ECM in obesity visceral white adipose tissueExperiments in human cellsCellular senescencePaper
The Journal of Biological Chemistry·Oct 7A PrP EGFR signaling axis controls neural stem cell senescence through modulating cellular energy pathwaysExperiments in mouse cellsCellular senescencePaper
Free Radical Biology & Medicine·Sep 23Mitochondria pleiotropism in stem cell senescence: Mechanisms and therapeutic approachesReviewCellular senescencePaper
Redox Biology·Sep 11FGF21 alleviates adipose stem cell senescence via CD90 glycosylation-dependent glucose influx in remodeling healthy white adipose tissueExperiments in miceInterventionsPaper
Genes & Diseases·Aug 9Epigenetic regulation of mesenchymal stem cell aging through histone modificationsReviewHistone modification and chromatin remodelingPaper
Research·Jul 31MAVS Antagonizes Human Stem Cell Senescence as a Mitochondrial StabilizerExperiments in human cellsCellular senescencePaper
Stem Cells and Development·Jul 27Senescent Stem Cell Dysfunction and Age-Related DiseasesReviewCellular senescencePaper
Oral Diseases·Jul 14Melatonin attenuates dental pulp stem cells senescence due to vitro expansion via inhibiting MMP3Experiments in human cellsMelatoninPaper
European Review for Medical and Pharmacological Sciences·Jul 4Partial cellular reprogramming stably restores the stemness of senescent epidermal stem cellsExperiments in cellsPartial reprogrammingPaper
Developmental Cell·Jun 16Restoration of CPEB4 prevents muscle stem cell senescence during agingExperiments in mouse cellsMusclePaper
Biochemical and Biophysical Research Communications·Jun 4BTG2 acts as an inducer of muscle stem cell senescenceExperiments in mouse cellsCellular senescencePaper
Antioxidants·May 27YAP Inhibition Alleviates Simulated Microgravity-Induced Mesenchymal Stem Cell Senescence via Targeting Mitochondrial DysfunctionExperiments in human cellsCellular senescencePaper
Cellular Signalling·May 22Brain-derived neurotrophic factor promotes orthodontic tooth movement by alleviating periodontal ligament stem cell senescenceExperiments in miceInterventionsPaper
Aging and Disease·May 17Mesenchymal Stem Cell Senescence during Aging:From Mechanisms to Rejuvenation StrategiesReviewCellular senescencePaper
Biomaterials Science·May 9Anti-aging biomaterial sturgeon chondroitin sulfate upregulating anti-oxidant and SIRT-1/c-fos gene expression to reprogram stem cell senescence and prolong longevityExperiments in miceInterventionsPaper
bioRxiv·Apr 25Chromatin condensation delays human mesenchymal stem cells senescence by safeguarding nuclear damages during long term in vitro expansionPreprint: experiments in human cellsCellular senescencePaper