Stem cell factor

3 papers2 findings

Humans2
Animals1

Interventions

1

Intermittent fasting

upin humans1

1 study

Intermittent fasting increases stem cell factor in humans.
“plasma, collected at D30 of fasting that contained a higher concentration of SCF and G-CSF”
HumansRamadan fastingplasma30 daysmalesn = 10
Intermittent Fasting During Ramadan Increases the Absolute Number of Circulating Progenitor Stem Cells in Healthy Subjects
Stem cells and developmentDec 4, 2024

More on Intermittent fasting

Upstream

1

Frailty

upin humans1

1 study

Frailty increases stem cell factor in humans (β = 0.527, Praw = 0.005, PFDR = 0.204).
“increased levels of stem cell factor (SCF, β = 0.527, Praw = 0.005, PFDR = 0.204)”
Humansgenetically predicted
Genetic insights into the causal linkage between systemic inflammatory regulators and frailty
CytokineOct 23, 2024

Funding

1 grant since 2021

National Heart, Lung, and Blood InstituteUS$1.5m

Cardiac Patches Loaded with Stem Cell Factors to Treat Heart Failure
National Heart, Lung, and Blood InstituteColumbia Univ New York MorningsideUS$310.5k2019–2024

Latest

2 in 12 months

Science AdvancesJun 27

Age-related decline in niche self-renewal factors drives testis aging via Hairless, Imp, and Chinmo

Experiments in fliesReproductive system

Aging CellFeb 14

The HIF-1α Pathway Regulates Satellite Cell Fate During Aging Through Histone Lactylation

Experiments in mouse cellsCell cycle regulation

bioRxivJun 5

Senescent mast cells contribute to the progression of benign prostatic hyperplasia via SCF/c-KIT mediated endothelial-mesenchymal transition

Preprint: study in peopleCellular senescence

American Journal of Reproductive ImmunologyJun 2

The Impacts of TNF-α-Induced Inflammation on Amnion Epithelial Cells: Exploring Stem Cell Gene Expression, Senescence, Inflammatory Responses, and Cellular Transition

Experiments in human cellsCellular senescence

International Journal of Molecular SciencesMay 28

Preconditioning with Rapamycin Improves Therapeutic Potential of Placenta-Derived Mesenchymal Stem Cells in Mouse Model of Hematopoietic Acute Radiation Syndrome

Experiments in miceRapamycin

PNASMar 10

Periarteriolar niches become inflamed in aging bone marrow, remodeling the stromal microenvironment and depleting lymphoid progenitors

Experiments in miceMechanisms

Stem Cells and DevelopmentDec 4

Intermittent Fasting During Ramadan Increases the Absolute Number of Circulating Progenitor Stem Cells in Healthy Subjects

Cohort study of 10 peoplePopulations

CytokineOct 23

Genetic insights into the causal linkage between systemic inflammatory regulators and frailty

Mendelian randomization in peopleInflammation

PLOS OneSep 11

Transcriptional control of a stem cell factor nucleostemin in liver regeneration and aging

Experiments in miceMechanisms

BiomoleculesJul 27

Single-Cell RNA Sequencing Reveals Immunomodulatory Effects of Stem Cell Factor and Granulocyte Colony-Stimulating Factor Treatment in the Brains of Aged APP/PS1 Mice

Experiments in miceInterventions