1 paper
In mice, genetically removing the protein reduced signs of cellular aging across multiple tissues and limited hallmarks of blood stem cell aging.In mice, genetically removing the protein reduced signs of cellular aging across multiple tissues and limited hallmarks of blood stem cell aging.
Mutant blood cells induced stromal senescence, while depleting senescent non-haematopoietic cells reduced clonal burden and delayed progression to myeloid neoplasia in…Mutant blood cells induced stromal senescence, while depleting senescent non-haematopoietic cells reduced clonal burden and delayed progression to myeloid neoplasia in mice.
Increasing histone 3 lysine 9 methylation reduced leukemogenesis in both young and aged murine cells.Increasing histone 3 lysine 9 methylation reduced leukemogenesis in both young and aged murine cells.