SPISE

3 papers2 findings

Humans3

Effects

1

Gestational diabetes mellitus

mediatesin humans1

1 study

SPISE mediates gestational diabetes mellitus in humans (43.65%).
Humansin statistical mediation modelsfemalesn = 586
First-trimester SPISE mediates the association between early-pregnancy body fat percentage change and gestational diabetes mellitus: an exploratory secondary analysis of a prospective cohort
Frontiers in endocrinology9 Sep 2026

More on Gestational diabetes mellitus

Associations

1

Gestational diabetes mellitus

downin humans1OR 0.127

1 study

SPISE lowers the risk of gestational diabetes mellitus in humans (OR 0.127, 95% CI 0.049-0.328).
HumansSPISE below threshold of 7.089femalesn = 586
First-trimester SPISE mediates the association between early-pregnancy body fat percentage change and gestational diabetes mellitus: an exploratory secondary analysis of a prospective cohort
Frontiers in endocrinology9 Sep 2026

More on Gestational diabetes mellitus

Latest

6 in 12 months

Journal of the American Heart Association26 Sep

Variations in Single-Point Insulin Sensitivity Estimator Index and the Risk of Cardiovascular Disease in Individuals With Cardiovascular-Kidney-Metabolic Syndrome Stages 0 to 3: A National Longitudinal Cohort Study

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Medical Sciences24 Sep

Technostress and Insulin Resistance Risk: A Cross-Sectional Analysis of 104,175 Spanish Workers Using TyG, TyG-BMI, METS-IR, and SPISE Indices

Cross-sectional study of 104,175 peopleInsulin resistance

Frontiers in Endocrinology24 Sep

First-trimester SPISE mediates the association between early-pregnancy body fat percentage change and gestational diabetes mellitus: an exploratory secondary analysis of a prospective cohort

Cohort study of 586 peopleGestational diabetes mellitus

Frontiers in Endocrinology15 Sep

Short- and long-term associations of insulin resistance indices with cardiovascular-kidney-metabolic syndrome risk: a retrospective cohort study

Cohort study of 12,334 peopleCardiovascular-kidney-metabolic syndrome

Nutricion Hospitalaria25 Aug

Associations of cumulative exposure and control patterns of the single-point insulin sensitivity estimator with incident cardiovascular disease in middle-aged and older Chinese adults with dysglycemia

Cohort study of 2,598 peopleCardiovascular disease

ADA Scientific Sessions 2026 Abstract5 Jun

Comparison of Surrogate Indexes of Insulin Resistance as Predictors of Diabetes: Analysis of Five U.S. Cohorts

Study in peopleBiomarkers