Mitochondrial DNA somatic mutation

mito-nuclear mismatch is associated with mitochondrial DNA somatic mutation in mice.

“mismatching between nuclear and mitochondrial ancestry impacts the somatic evolution of the mitochondrial genome in different tissues throughout ageing.”

Animalsthree tissues

Mitochondrial haplotype and mito-nuclear matching drive somatic mutation and selection throughout ageing

Nature ecology & evolution·15 Feb 2024