Somatic mosaicism

1 paper

Humans1

Latest

20 in 12 months

Cell3 h

First body-wide map charts genetic differences in human cells

The paper describes a research network’s map of mutations acquired during life, providing a reference for testing their roles in aging and disease.The paper describes a research network’s map of mutations acquired during life, providing a reference for testing their roles in aging and disease.

Study in peopleAI & data

Cell3 h

DNA methods appear complementary in human cells and tissues

Benchmarks using human cell lines and donor tissues produced data for nine samples and suggested that three DNA analysis approaches offer complementary information.Benchmarks using human cell lines and donor tissues produced data for nine samples and suggested that three DNA analysis approaches offer complementary information.

Study of 9 peopleAI & data

The European Journal of Neuroscience18 Sep

Somatic Mosaicism of the Brain: The Functional Implications of Post-Zygotic Mutations to Neural Circuits

ReviewMechanisms

Brain Communications17 Sep

Alzheimer's disease: genetic background in the era of next-generation sequencing technologies

ReviewMechanisms

Nature Reviews Neurology15 Sep

Somatic mosaicism in the brain: linking development, ageing and neurodegeneration

ReviewMechanisms

bioRxiv3 Sep

Integrated map of somatic mosaicism across human tissues in 25 individuals

Preprint: cohort study of 25 peopleAI & data

Life Sciences28 Aug

Somatic genomic mosaicism in chronic kidney disease progression: A graded appraisal of renal epithelial injury, cellular senescence, and therapeutic implications

Systematic review of observational studiesKidney

Ageing Research Reviews25 Aug

Somatic mutations in human ontogenesis and their impact on health

ReviewMechanisms

Genome Biology25 Aug

Determinants of mutation susceptibility along the genome are largely invariant across human tissues

Computational studyAI & data

arXiv10 Aug

Comparing Tobit and Two-Part Hurdle Models for Semi-Continuous Longitudinal Data with an Application to Clonal Hematopoiesis

Preprint: computational studyMechanisms