Smad2/3 phosphorylation

1 paper1 finding

Animals1

Interventions

1

SIS3

downin mice1

1 study

SIS3 inhibits Smad2/3 phosphorylation in mice.
“pharmacological inhibition by SIS3 abolishing Sarm1-driven Smad2/3 phosphorylation.”
AnimalsSarm1 overexpression
Sarm1-containing extrachromosomal circular DNA promotes aging-associated cardiac fibrosis via TGF-β/Smad activation
Journal of molecular cell biology2 Mar 2026

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Journal of Molecular Cell Biology2 Mar

Sarm1-containing extrachromosomal circular DNA promotes aging-associated cardiac fibrosis via TGF-β/Smad activation

Experiments in miceMechanisms

International Journal of Molecular Sciences30 Dec

Atelocollagen Increases Collagen Synthesis by Promoting Glycine Transporter 1 in Aged Mouse Skin

Experiments in miceSkin

Research4 Aug

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Experiments in animalsMechanisms