Sirtuin activity
- Animals1
Funding
3 grants since 2024National Institute of Environmental Health SciencesUS$3.3mNational Institute on AgingUS$455.8kVeterans Affairs
PKG Regulation of Sirtuin 1 as a Novel Treatment Strategy for Age-related Osteoporosis
National Institute on AgingUniversity of California, San DiegoUS$455.8k2021–2027
Sirtuins in Lung Aging and Fibrosis
Veterans AffairsSoutheast Louisiana Veterans Health Care2016–2025
Sirtuins and nuclear receptors in aging and age-associated diseases
National Institute of Environmental Health SciencesNational Institute of Environmental Health SciencesUS$3.3m
Latest
2 in 12 monthsExpert Opinion on Therapeutic Targets
Sirtuin signaling as therapeutic targets of immunosenescence
ReviewInterventions
Clinical and Experimental Reproductive Medicine
The impact of nicotinamide mononucleotide on ovarian health: A comprehensive literature review of preclinical evidence and therapeutic potential
GSA 2024 Abstract
THE EFFECT OF PICEATANNOL FROM PASSION FRUIT SEED EXTRACT ON SIRTUIN EXPRESSION
Trial in peopleInterventions
Nature
Lithocholic acid binds TULP3 to activate sirtuins and AMPK to slow down ageing
Experiments in miceInterventions
Cardiovascular Research
Empagliflozin inhibits excessive autophagy through the AMPK/GSK3β signalling pathway in diabetic cardiomyopathy
Experiments in miceSGLT2 inhibitors
Nature Reviews Molecular Cell Biology
Slowing ageing by design: the rise of NAD⁺ and sirtuin-activating compounds
ReviewInterventions
Trends in Endocrinology and Metabolism
SIRT1 and other sirtuins in metabolism
ReviewSirtuin signalling