SERPINE1 expression
1 paper1 finding
- Cells1
Interventions
1Substrate stiffness
upin human cells1
1 study
Substrate stiffness
upin human cells1
Substrate stiffness increases SERPINE1 expression in human cells.
“Stiff substrates also increased SERPINE1 expression and its colocalization with actin fibers, with stronger responses observed in senescent than in young fibroblasts.”
Cellsstronger responses in senescent than young fibroblaststunable polyacrylamide hydrogelsfibroblast
SERPINE1–AP2A1 interplay links substrate stiffness to fibroblast senescence
bioRxiv (Cold Spring Harbor Laboratory)1 Jul 2026Preprint
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