Salivary lactoferrin

There are 4 papers on salivary lactoferrin in aging research: 1 trial and 3 observational studies in people.

Biomarker

4 papers study it1 more mentions it6 findings

1 new paper in 30 daysSee all 5 papers on salivary lactoferrin

“sLF was negatively associated with Aβ load in parieto-temporal regions.”
Salivary lactoferrin is associated with cortical amyloid-beta load, cortical integrity, and memory in agingAlzheimer's research & therapy2021doi:10.1186/s13195-021-00891-8
  • Human trial1
  • Humans3

Upstream

1

Menopause

no changein humans1

1 study
  1. Menopause was not clearly linked with salivary lactoferrin in humans (Menopausal versus premenopausal women with clinically healthy periodontal tissues).

    “no statistically significant differences for pH, lactoferrin, lysozyme, and IgA values were found.”

    HumansMenopausal versus premenopausal women with clinically healthy periodontal tissuessalivafemalesn = 30

    Salivary Flow, Biochemical Profile and Selected Antibacterial Properties of Saliva in Menopausal Women

    Journal of clinical medicine

More on Menopause

Associations

5

Digit Span Memory Test scores

mixedin humans1

1 study
  1. Salivary lactoferrin is associated with digit Span Memory Test scores in humans.

    “we found a significant r between sLF and Digit Span Memory Test (DSMT) scores (P = 0.013)”

    HumansAt risk for Alzheimer's disease due to parental history; adjusted for age, sex, race, and years of educationsalivan = 17

    Pilot: Salivary Lactoferrin as a Biomarker of Alzheimer's Disease

    medRxiv : the preprint server for health sciencesPreprint

Memory

downin humans1

1 study
  1. Salivary lactoferrin is associated with memory in humans (cognitively normal).

    “increased FDG uptake in the posterior cingulate cortex, and poorer memory.”

    Humanscognitively normaln = 74

    Salivary lactoferrin is associated with cortical amyloid-beta load, cortical integrity, and memory in aging

    Alzheimer's research & therapy

glucose metabolism

upin humans1

1 study
  1. Salivary lactoferrin is associated with glucose metabolism in humans (cognitively normal).

    “increased FDG uptake in the posterior cingulate cortex, and poorer memory.”

    Humanscognitively normalposterior cingulate cortexn = 74

    Salivary lactoferrin is associated with cortical amyloid-beta load, cortical integrity, and memory in aging

    Alzheimer's research & therapy

Cortical thickness

upin humans1

1 study
  1. Salivary lactoferrin is associated with cortical thickness in humans (cognitively normal).

    “Moreover, sLF was related to thickening of the middle temporal cortex”

    Humanscognitively normalmiddle temporal cortexn = 74

    Salivary lactoferrin is associated with cortical amyloid-beta load, cortical integrity, and memory in aging

    Alzheimer's research & therapy

More on Cortical thickness

Amyloid-beta

downin humans1

1 study
  1. Salivary lactoferrin is associated with amyloid-beta in humans (cognitively normal).

    “sLF was negatively associated with Aβ load in parieto-temporal regions.”

    Humanscognitively normalparieto-temporal regionsn = 74

    Salivary lactoferrin is associated with cortical amyloid-beta load, cortical integrity, and memory in aging

    Alzheimer's research & therapy

More on Amyloid-beta

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