FDG uptake

1. FDG uptake is associated with mortality in humans (memory clinic patients with PET) (HR 0.68 [0.55–0.84]).

   “In patients with PET (N=218), FDG uptake in the left IFG (pars opercularis) was a significant predictor (HR=0.68 [0.55–0.84], FWEc p<0.05).”

   Humansmemory clinic patients with PETleft inferior frontal gyrus, pars opercularisn = 218

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1. FDG uptake is associated with fractional anisotropy in humans (0.32 ≤ r ≤ 0.71).

   “relative FDG uptake in both origin and target clusters correlated positively with FA (0.32 ≤ r ≤ 0.71)”

   Humansbrainn = 94

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More on Fractional anisotropy

1. ECog memory domain score is associated with FDG uptake in normal aging adults and patients with early stage probable AD (rho = -0.41 and -0.46, P < 0.01).

   “The memory domain of the ECog scale was significantly correlated with FDG uptake in the angular gyrus and posterior cingulum gyrus (rho = -0.41 and -0.46, P < 0.01).”

   Humansin normal aging adults and patients with early stage probable ADangular gyrus and posterior cingulum gyrus

   Everyday cognition scales are related to cognitive function in the early stage of probable Alzheimer's disease and FDG-PET findings

   Scientific reports·May 11, 2017

More on ECog memory domain score