REM sleep

Biomarker

2 papers

  • Humans2

Funding

1 grant since 2025

National Institute on AgingUS$2.3m

Latest

Nov 2025: 1Dec 2025: 9Jan 2026: 2Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 1Jul 2026: 0Aug 2026: 9Sep 2026: 8Oct 2026: 535 in 12 months
Alzheimer's Research & Therapy

Probable REM sleep disorder links to Lewy body dementia

In a memory clinic cohort, probable REM sleep behaviour disorder was linked to incident Lewy body dementia with a hazard ratio of 4.82.In a memory clinic cohort, probable REM sleep behaviour disorder was linked to incident Lewy body dementia with a hazard ratio of 4.82.

Cohort study of 5,274 peopleDementia
Sleep Medicine

Dopamine loss in sleep disorder predicts Parkinson conversion

In PET scans of 77 patients with isolated REM sleep behavior disorder, quantitative dopamine markers showed intermediate loss and predicted phenoconversion toward…In PET scans of 77 patients with isolated REM sleep behavior disorder, quantitative dopamine markers showed intermediate loss and predicted phenoconversion toward Parkinson's disease.

Cohort study of 194 peopleParkinson's disease
Journal of Neurology

Multimodal PET and MRI predict dementia with Lewy bodies

Combined occipito-parietal cortex pathology and striatal dopamine loss predicted conversion to dementia with Lewy bodies with a sub-distribution hazard ratio of 38.68.Combined occipito-parietal cortex pathology and striatal dopamine loss predicted conversion to dementia with Lewy bodies with a sub-distribution hazard ratio of 38.68.

Cohort study of 21 peopleDementia with Lewy bodies