Proportion of C9orf72 expansions with 500–1500 repeats

Biomarker

1 paper1 finding

Humans1

Associations

Age at sampling

mixedin humans1

1 study

Age at sampling is associated with proportion of C9orf72 expansions with 500–1500 repeats in humans.
“The proportion of shorter repeats ([500-1500 repeats]) increased with the age at sampling in ALS patients but decreased in presymptomatic and FTD cohorts”
HumansPositive association in amyotrophic lateral sclerosis; negative association in presymptomatic carriers and frontotemporal dementiablood
Links between age and blood DNA repeats differ by disease
medRxiv7 Oct 2026Preprint

Latest

1 in 12 months

medRxiv7 Oct

Links between age and blood DNA repeats differ by disease

An observational preprint analysed blood from 54 people carrying expanded DNA repeats, including people with amyotrophic lateral sclerosis, frontotemporal dementia or no…An observational preprint analysed blood from 54 people carrying expanded DNA repeats, including people with amyotrophic lateral sclerosis, frontotemporal dementia or no symptoms.

Preprint: cross-sectional study of 54 peopleMechanisms

Paper

Proportion of C9orf72 expansions with 500–1500 repeats

Associations

Latest

Links between age and blood DNA repeats differ by disease

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