1 paper2 findings
Age at sampling
no changein humans1
Age at sampling has no effect on proportion of C9orf72 expansions exceeding 2000 repeats in humans.
“conversely to patients with ALS (p = 0.98).”
HumansPatients with amyotrophic lateral sclerosis; particularly expansions exceeding 4000 repeatsbloodn = 22
Links between age and blood DNA repeats differ by disease
medRxiv7 Oct 2026Preprint
Age at sampling
upin humans1
Age at sampling is associated with proportion of C9orf72 expansions exceeding 2000 repeats in humans.
“increased along with the age at sampling in presymptomatic carriers and FTD cases (p <1.10-e4 and p = 0.006 respectively)”
HumansPresymptomatic carriers and frontotemporal dementia cases; particularly expansions exceeding 4000 repeatsblood
Links between age and blood DNA repeats differ by disease
medRxiv7 Oct 2026Preprint
An observational preprint analysed blood from 54 people carrying expanded DNA repeats, including people with amyotrophic lateral sclerosis, frontotemporal dementia or no…An observational preprint analysed blood from 54 people carrying expanded DNA repeats, including people with amyotrophic lateral sclerosis, frontotemporal dementia or no symptoms.