Papers on progranulin
54 papers1 new in 30 days
Sunday, November 27
Thursday, August 4
Saturday, January 22
International Journal of Molecular Sciences
Analysis of the Biomarkers for Neurodegenerative Diseases in Aged Progranulin Deficient Mice
Experiments in miceMechanisms
Monday, January 17
The Journals of Gerontology, Series A
Interactions Between Weight Loss and Plasma Neurodegenerative Markers for Determining Cognitive Decline Among Community-Dwelling Older Adults
Cohort study of 470 peopleBiomarkers
Saturday, December 25
Journal of Neuroinflammation
Microglia and astrocyte involvement in neurodegeneration and brain cancer
ReviewMechanisms
Thursday, December 16
Journal of the American Geriatrics Society
Associations of plasma neurofilament light chain and progranulin with frailty in older adults
Cohort study of 507 peopleNfL
Monday, November 29
Molecular Neurodegeneration
A panel of CSF proteins separates genetic frontotemporal dementia from presymptomatic mutation carriers: a GENFI study
Cohort study of 221 peopleFrontotemporal dementia
Sunday, September 5
The Journal of Biological Chemistry
Spreading of Alzheimer tau seeds is enhanced by aging and template matching with limited impact of amyloid-β
Experiments in miceMechanisms
Saturday, August 21
Scientific Reports
AZP2006, a new promising treatment for Alzheimer's and related diseases
Experiments in animalsAlzheimer's disease
Wednesday, August 11
Journal of Neuropathology and Experimental Neurology
Loss of Lysosomal Proteins Progranulin and Prosaposin Associated with Increased Neurofibrillary Tangle Development in Alzheimer Disease
Cross-sectional study in peopleMechanisms
Thursday, January 21
Friday, January 15
Neurotoxicity Research
Sleep Characteristics and Cerebrospinal Fluid Progranulin in Older Adults: The CABLE Study
Study in peoplePopulations
Saturday, November 14
The Journals of Gerontology, Series A
Cross-Sectional and Longitudinal Associations Between Plasma Neurodegenerative Biomarkers and Physical Performance Among Community-Dwelling Older Adults
Cohort study of 507 peopleBiomarkers
Friday, September 4
PLOS One
Serum progranulin levels are associated with frailty in middle-aged individuals
Cohort study of 358 peopleBiomarkers
Wednesday, August 12
Journal of Neuroinflammation
Microglial burden, activation and dystrophy patterns in frontotemporal lobar degeneration
Study in peopleMechanisms
Wednesday, January 22
Nature Neuroscience
Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain
Study in peopleLipid droplet
Tuesday, December 24
Journal of Molecular and Cellular Cardiology
Progranulin deficiency leads to enhanced age-related cardiac hypertrophy through complement C1q-induced β-catenin activation
Experiments in miceComplement system
Saturday, November 17
bioRxiv
C. elegans granulins promote an age-associated decline in protein homeostasis via lysosomal protease inhibition
Preprint: experiments in wormsProteostasis
Wednesday, October 3
Aging and Disease
Progranulin Deficient Mice Develop Nephrogenic Diabetes Insipidus
Experiments in miceMechanisms
Friday, August 3
Ageing Research Reviews
Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases
Systematic reviewBiomarkers
Wednesday, May 10
Experimental Gerontology
Involvement of progranulin in modulating neuroinflammatory responses but not neurogenesis in the hippocampus of aged mice
Experiments in miceInflammation
Saturday, January 28
Acta Neuropathologica Communications
Elevated TMEM106B levels exaggerate lipofuscin accumulation and lysosomal dysfunction in aged mice with progranulin deficiency
Experiments in miceAutophagy
Thursday, June 3
The American Journal of Pathology
Accelerated lipofuscinosis and ubiquitination in granulin knockout mice suggest a role for progranulin in successful aging
Experiments in miceMechanisms