Journal of Neuropathology and Experimental Neurology
Gene variant linked to brain changes and cancer in opposite ways
Each extra copy was linked to lower odds of cancer history, with an odds ratio of 0.91 compared with one fewer copy.Each extra copy was linked to lower odds of cancer history, with an odds ratio of 0.91 compared with one fewer copy.
Genetic association studyMechanisms
Who was studiedParticipants of European ancestry
What changedEach additional T copy was linked to higher odds of brain abnormalities (odds ratio 1.42) and lower cancer odds (0.91)
The catchCancer history relied on clinician reports, which could miss unreported cancers