Pro-inflammatory cytokines
Biomarker2 papers1 finding
- Animals1
Interventions
1Astrocyte-conditioned solution
downin mice1
1 study
Astrocyte-conditioned solution
downin mice1
Astrocyte-conditioned solution decreases pro-inflammatory cytokines in mice.
Animals
Astrocytic secretome enhances hippocampal neurogenesis and spatial memory in mice · bioRxiv · 29 Sep 2026 · Preprint
Latest
10Structured exercise reduces heart fat and an inflammatory marker in older adults
A 12-month randomized trial showed greater drops in epicardial adipose volume with more weekly sessions alongside lower circulating M-CSF levels.
Frontiers in public health · Xue X et al.
Neuroinflammation and Autophagy in Neurodegeneration: Cellular Mechanisms and Therapeutic Strategies
Astrocytic secretome enhances hippocampal neurogenesis and spatial memory in mice
Treatment with astrocyte-conditioned solution also rescued cognitive deficits and lowered inflammation in mouse models of Alzheimer's disease.
bioRxiv · Vilademunt M et al.
[Mechanisms of cGAS-STING-mediated chronic inflammation and targeted interventions in brain aging]
Crebanine protects aged rats from anesthesia-induced cognitive deficits by restoring mitophagy
The compound suppresses mitochondrial DNA leakage and the cGAS-STING inflammatory pathway in microglial cells following sevoflurane exposure.
Research Square · Zheng G et al.
Persistent interferon-gamma fuels chronic cardiac remodeling after heart attacks in aged mice
A conserved interferon-gamma signature and heightened T cell recruitment drive worse long-term heart failure outcomes in older mice following myocardial infarction.
Journal of molecular and cellular cardiology · Melika ET et al.