Astrocyte-conditioned solution

Intervention1 paper4 findings

Outcomes

Pro-inflammatory cytokines

downin mice1

1 study

Astrocyte-conditioned solution decreases pro-inflammatory cytokines in mice.
Animals
Astrocytic secretome enhances hippocampal neurogenesis and spatial memory in mice · bioRxiv · 29 Sep 2026 · Preprint

Spatial memory

upin mice1

1 study

Astrocyte-conditioned solution improves spatial memory in mice.
Animalsin APP/PS1 mice
Astrocytic secretome enhances hippocampal neurogenesis and spatial memory in mice · bioRxiv · 29 Sep 2026 · Preprint

Cognitive function

upin mice1

1 study

Astrocyte-conditioned solution improves cognitive function in mice.
Animalsin THY-Tau22 mice
Astrocytic secretome enhances hippocampal neurogenesis and spatial memory in mice · bioRxiv · 29 Sep 2026 · Preprint

Adult hippocampal neurogenesis

upin mice1

1 study

Astrocyte-conditioned solution increases adult hippocampal neurogenesis in mice.
Animalsin young and aged wild-type micehippocampus
Astrocytic secretome enhances hippocampal neurogenesis and spatial memory in mice · bioRxiv · 29 Sep 2026 · Preprint

AnimalsPreprintBrain aging30 Sep

Treatment with astrocyte-conditioned solution also rescued cognitive deficits and lowered inflammation in mouse models of Alzheimer's disease.

bioRxiv · Vilademunt M et al.