Platelet to white blood cell ratio

1. Platelet to white blood cell ratio is linked with a lower risk of type 2 diabetes in humans (highest vs. lowest quartile) (HR 0.760, 95% CI 0.615-0.940, P = 0.011).

   “Participants in the highest PWR quartile had a 24.0% lower risk (HR 0.760, 95% CI 0.615-0.940, P = 0.011) compared to the lowest quartile.”

   Humanshighest vs. lowest quartilen = 7,571

   A community‑based study of platelet‑to‑white blood cell ratio and new‑onset type 2 diabetes in older adults

   BMC endocrine disorders·Apr 13, 2026

More on Type 2 diabetes

1. Platelet to white blood cell ratio is associated with sarcopenic obesity in humans under waist circumference classification (OR = 0.621, 95% CI: 0.390–0.988).

   “but inversely associated with PWR (OR = 0.621, 95% CI: 0.390–0.988; P = 0.040)”

   Humansunder waist circumference classificationn = 1,009

   Systemic inflammatory indices SIRI, AISI, and PWR are associated with sarcopenic obesity in middle-aged and older chinese adults: a cross-sectional study

   Nutrition & metabolism·Mar 26, 2026

More on Sarcopenic obesity

1. Platelet to white blood cell ratio is associated with total skeletal muscle mass index in humans (multivariate linear regression) (beta = -0.0051 (95% CI: -0.0102 to -0.0001)).

   “PWR were associated with low TSMI, with coefficients of -0.0091 (95% confidence interval [ CI]: -0.0142 to -0.0041), -0.0119 (95% CI: -0.0170 to -0.0068), and -0.0051 (95% CI: -0.0102 to -0.0001)”

   Humansmultivariate linear regressionn = 4,033

   Associations of White Blood Cell, Platelet Count, Platelet-to-White Blood Cell Ratio with Muscle Mass among Community-Dwelling Older Adults in China

   Biomedical and environmental sciences : BES·Jun 20, 2025

1. Platelet to white blood cell ratio is linked with a lower risk of chronic kidney disease in humans (OR 0.59, 95% CI 0.46-0.76).

   “In the full model, the odds ratios (ORs) of prevalent CKD were 0.78 (95% CI = 0.62-0.97, p < 0.05) for the T2 group and 0.59 (95% CI = 0.46-0.76, p < 0.001) for the T3 group.”

   Humans

   The Association between the Platelet to White Blood Cell Ratio and Chronic Kidney Disease in an Aging Population: A Four-Year Follow-Up Study

   Journal of clinical medicine·Nov 13, 2023

More on Chronic kidney disease

1. Platelet to white blood cell ratio is associated with sarcopenia in humans (OR 1.57, 95% CI 1.03–2.40).

   “This association remained significant in the fully adjusted model [OR (95%CI) =1.82 (1.20 to 2.78), p-value =0.005 for PLT; OR (95%CI) =1.57 (1.03 to 2.40), p-value =0.035 for PWR].”

   Humans

   Association between platelet, white blood cell count, platelet to white blood cell ratio and sarcopenia in community-dwelling older adults: focus on Bushehr Elderly Health (BEH) program

   BMC geriatrics·Apr 8, 2022

More on Sarcopenia

1. Platelet to white blood cell ratio is linked with a lower risk of hemorrhagic stroke in humans (increase of 20% for PWR) (aHR = 0.47, 95% CI 0.22–0.95).

   “significant associations were observed in those with an increase of 20% for the PWR with the risk of fatal haemarragic stroke (aHR = 0.47, 95% CI 0.22–0.95)”

   Humansincrease of 20% for PWRn = 27,811

   Association of platelet-to-white blood cell ratio and platelet-to-neutrophil ratio with the risk of fatal stroke occurrence in older Chinese

   Research Square·Mar 9, 2022Preprint

More on Hemorrhagic stroke

1. Platelet to white blood cell ratio is linked with a lower risk of stroke mortality in humans (aHR = 0.73, 95% CI 0.53-1.00).

   “A decreased risk of fatal all stroke showed in those with the highest quartiles for both the PWR (aHR = 0.73, 95% CI 0.53-1.00)”

   Humansn = 27,811

   Association of platelet-to-white blood cell ratio and platelet-to-neutrophil ratio with the risk of fatal stroke occurrence in older Chinese

   Research Square·Mar 9, 2022Preprint