In an observational study of 1,297 people without dementia, combined brain and blood measures showed the strongest links to disease progression.In an observational study of 1,297 people without dementia, combined brain and blood measures showed the strongest links to disease progression.
A cross-sectional analysis of 15,612 adults aged 55–80 screened for Alzheimer’s trials found blood marker differences between racial and ethnic groups.A cross-sectional analysis of 15,612 adults aged 55–80 screened for Alzheimer’s trials found blood marker differences between racial and ethnic groups.
Each standard deviation decrease in locus coeruleus intensity was associated with 53% higher odds of testing positive for an Alzheimer's blood marker.Each standard deviation decrease in locus coeruleus intensity was associated with 53% higher odds of testing positive for an Alzheimer's blood marker.
In 602 discovery and 2,313 validation participants, associations between plasma pTau217 and brain pathology were stronger among people with lower periventricular…In 602 discovery and 2,313 validation participants, associations between plasma pTau217 and brain pathology were stronger among people with lower periventricular diffusivity.